The anti-root-knot nematode is an agricultural microbial preparation made by hebi Renyuan Biological technology Development Co., LTD., which USES the international leading scientific and technological achievements of the line worm, selects a variety of effective strains such as Bacillus, Paecilomyces, and then assists special synergistic agent, and adopts modern microbial fermentation technology to process and prepare. This product has a good control effect on crop nematode disease, especially on root knot nematode, cyst nematode, stem nematode and other soil parasitic nematode effect. This bacterial agent is a living nematode killer. Its effective fungus hypha can invade the c. elegans and reproduction within the egg has a strong affinity to nematodes tubulin, with its unique hyphae penetrate worm shell body, make the lipid layer and chitin disintegration, and form into balls and vegetative hyphae, absorption of the worm body inclusions, insect body skin and somatic shrinking fast dehydration, and then death, of adult worms and eggs have effect. This product not only effectively prevents and controls root knot nematode disease, but also prevents root rot disease, wilt disease, verticillium wilt disease, vertical blight disease and other soil-borne diseases. It is suitable for controlling root knot nematode diseases in vegetables, fruit trees,melons, tobacco and peanuts.